The GABPA Antibody from MyBioSource.com is a Mouse Monoclonal antibody to GABPA, and NRF2A. This antibody recognizes Human, and Mouse antigen. The GABPA Antibody has been validated for the following applications: ELISA, Immunofluorescence, and Western Blot.
Description
Background: GABPA: GA binding protein transcription factor, alpha subunit 60kDa. It is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, it may play a role in the Down Syndrome phenotype